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肿瘤

肿瘤(Tumor)是机体在各种致癌因素作用下,局部组织的某一个细胞在基因水平上失去对其生长的正常调控,导致其克隆性异常增生而形成的新生物。一般认为,肿瘤细胞是单克隆性的,即一个肿瘤中的所有瘤细胞均是一个突变的细胞的后代。

TLR-8 ligands Library DP8700 TLR-8配体化合物库 597 compounds Estrogen related receptor gamma (ERRγ) targeted library OA4100 ERRγ靶向化合物库 950 compounds Matrix metalloproteinase-2 (MMP2) targeted Library OA7400 MMP2靶标化合物库 726 compounds Proto-oncogene tyrosine protein kinase Fyn inhibitor library OT7300 原癌基因酪氨酸蛋白激酶 Fyn 抑制剂库 481 compounds Aurora A Kinase Targeted Library LF4200 Aurora A激酶靶向化合物库 590 compounds STING Targeted Library LF6900 STING靶向化合物库 1600 compounds Proto-oncogene tyrosine kinase ABL1 inhibitor library OA6500 原癌基因酪氨酸激酶 ABL1 抑制剂库 771 compounds Anti-Colorectal Cancer Compound Library L2194 抗结直肠癌化合物库 1880 compounds PD-1/L1 Library DP2450 PD-1/L1化合物库 500 compounds KRAS-Targeted Library DP3800 KRAS靶向化合物库 11000 compounds DNA Damage & Repair Compound Library L3900 DNA 损伤和修复分子库 1040 compounds Ubiquitination Compound Library L8600 泛素化化合物库 210 compounds Enhancer of Zeste Homolog 2 (EZH2) Targeted Library OA5500 EZH2靶标化合物库 979 compounds Cyclin-dependent kinase 2 (CDK2) inhibitor library OA2700 CDK2抑制剂库 670 compounds INTEGRIN Receptors Targeted library DP5700 整合素受体靶向化合物库 2000 compounds DOT1-like histone H3 methyltransferase (DOT1L) inhibitor library OA5400 DOT1L抑制剂库 622 compounds Microtubule-Targeted Compound Library L1110 微管靶向化合物库 142 compounds Cyclin-dependent Kinase 7 (CDK7) Screening Set LF1012 CDK7靶向化合物库 1300 compounds Histone acetyltransferase (HAT) inhibitor library OA5800 HAT抑制剂库 814 compounds Hippo Pathway Modulators Library US2700 Hippo调节剂库 2608 compounds Anti-Cancer Compound Library L2100 抗癌化合物库 8700 compounds Anti-Ovarian Cancer Compound Library L2196 抗卵巢癌化合物库 1867 compounds DNA Damage and Repair Compound Library Plus L3980 DNA损伤/修复库Plus 667 compounds Targeted Therapy Drug Library L2152 靶向治疗药物库 119 compounds Anti-Liver Cancer Compound Library L2193 抗肝癌化合物库 2000 compounds Aurora B Kinase Targeted Library LF4300 Aurora B激酶靶向化合物库 1000 compounds Poly (ADP-ribose) polymerase 1 (PARP-1) targeted library OA4300 PARP-1靶向化合物库 513 compounds DNA (cytosine-5)-methyltransferase 3 beta (DNMT3b) inhibitor library OA5300 DNMT3b抑制剂库 1261 compounds Anticarcinogenic library OT2500 抗癌化合物库OT 822 compounds CDK Focused Library PB1900 CDK靶点化合物库 1483 compounds Tubulin Inhibitors Library US4200 微管抑制剂库 2003 compounds Targeted Oncology Library AN5700 靶向肿瘤化合物库 4815 compounds Aurora A kinase inhibitor library OT3400 Aurora A激酶抑制剂库 364 compounds Lysine-specific demethylase 4A (KDM4A) Targeted Library LF5500 KDM4A靶向化合物库 2000 compounds Anticancer Screening Compound Library LF1600 抗癌筛选化合物库 13600 compounds Immuno-Oncology Compound Library L2170 肿瘤免疫治疗小分子化合物库 523 compounds DNA (cytosine-5)-methyltransferase 1 (DNMT1) inhibitor library OA5200 DNMT1抑制剂库 466 compounds Urokinase inhibitor library OT1120 Urokinase抑制剂库 Lysine-specific demethylase 4C (GASC1) Targeted Library OA6100 GASC1靶标化合物库 966 compounds Exosome Compound Library L9420 外泌体相关化合物库 76 compounds BRD4 targeted library DP5300 BRD4靶向化合物库 5000 compounds DCAFs focused ligands EN6900 DCAFs靶向配体库 5440 compounds Cyclin-dependent Kinase Focused Library LF1035 细胞周期蛋白依赖激酶靶向库 1700 compounds Arginase Targeted Library DD4700 精氨酸酶靶向化合物库 2000 compounds C-Met Library DP5560 c-Met靶向化合物库 16000 compounds Ligase Focused Screening Library LF5400 连接酶靶向化合物库 3900 compounds Akt-Targeted Library DP3200 Akt靶向化合物库 12000 compounds Death-associated kinase 2 (DAPK2) inhibitor library OA5100 DAPK2抑制剂库 591 compounds Anti-Lung Cancer Compound Library L2190 抗肺癌化合物库 2103 compounds Anti-Cancer Active Compound Library L2160 抗癌活性化合物库 3580 compounds Anti-Prostate Cancer Compound Library L2195 抗前列腺癌化合物库 2256 compounds Aurora B kinase inhibitor library OA4600 Aurora B激酶抑制剂库 508 compounds Cyclin-dependent Kinases 2 (CDK2) Focused Library LF4600 CDK2靶向化合物库 400 compounds Anti-Cancer Compound Library Plus L2180 抗肿瘤库Plus 1468 compounds Protein Arginine Methyltransferases (PRMTs) Targeted Library OA3000 PRMTs靶向化合物库 842 compounds Proto-oncogene tyrosine protein kinase Kit inhibitor library OT7400 原癌基因酪氨酸蛋白激酶试剂盒抑制剂库 214 compounds Anti-Cancer Approved Drug Library L2110 抗癌上市药物库 1779 compounds Aurora A-B Kinases Library DP4300 Aurora A-B激酶化合物库 10000 compounds Chemotherapy Drug Library L2151 化疗药物库 48 compounds Tubulin Library From Enamine EN4200 微管靶向化合物库EN 3200 compounds Metalloproteinase-9 targeted library OT6200 Metalloproteinase-9 靶标化合物库 608 compounds ALK Tyrosine Kinase Focused Library LF4100 ALK酪氨酸激酶靶向化合物库 2500 compounds STING Agonist Library DD3600 STING激动剂库 6368 compounds Antimitotic Tubulin Library DD1800 抗有丝分裂微管蛋白化合物库 18000 compounds MDM2 focused Library DP7690 MDM2靶向化合物库 6500 compounds Anti-Cancer Clinical Compound Library L2120 抗癌临床化合物库 2545 compounds DCLK1 Modulators Library US2300 DCLK1调节剂库 763 compounds ERK5 (MAPK7) Kinase Targeted Library LF4700 ERK5(MAPK7)靶向化合物库 900 compounds OA Hsp90 targeted library OA3700 Hsp90靶向化合物库OA 648 compounds Mitogen-activated protein kinase 1 (MAPK1 ERK2) inhibitor library OA2600 MAPK1 ERK2 抑制剂库 197 compounds Anti-Pancreatic Cancer Compound Library L2192 抗胰腺癌化合物库 2508 compounds Anti-Breast Cancer Compound Library L2191 抗乳腺癌化合物库 2440 compounds ERB Focused Library PB1800 ERB靶点化合物库 1922 compounds Aurora C kinase inhibitor library OT3500 Aurora C激酶抑制剂库 1162 compounds ADK Focused Library PB2200 ADK靶点化合物库 146 compounds Ligase-Targeted screening library VM1800 连接酶靶向筛选化合物库 7261 compounds Anti-Cancer Metabolism Compound Library L2130 抗癌细胞代谢库 1268 compounds Cancer Cell Differentiation Compound Library L2140 癌细胞分化化合物库 573 compounds CREB binding protein (CREBBP) targeted library OA5000 CREBBP靶向化合物库 576 compounds ADP-thymidine kinase inhibitor library OT8900 ADP-胸苷激酶抑制剂库 922 compounds P38 Focused Library PB1500 P38靶点化合物库 2775 compounds Vascular Endothelial Growth Factor Receptor Kinase 2 (VGFR-2) Focused Library LF5300 VEGFR2靶向化合物库 1000 compounds Anticancer Library DD1100 抗肿瘤筛选化合物库 65000 compounds Deubiquitinase Screening Libraries LF2600 去泛素化酶筛选化合物库 3300 compounds PDZ domain targeted library OA6300 PDZ结构域靶标化合物库 2010 compounds P21-activated kinase 1 (PAK1) inhibitor library OA6200 PAK1抑制剂库 606 compounds Anti-Cancer Drug Library L2150 抗癌药物库 3150 compounds DGK Inhibitors Library DP9200 DGK抑制剂库 12000 compounds Bromodomain-containing protein 4 (BRD4) inhibitor library OA4700 BRD4抑制剂库 401 compounds Hsp90-Targeted Library DP3500 Hsp90靶向化合物库 13000 compounds