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高通量/高内涵化合物库

高通量筛选,高内涵筛选(HTS,HCS)作为目前主流的药物筛选方法,具有微量、快速、灵敏和准确等优点,可同时筛选成千上万个样品。该技术非常依赖数量庞大且结构多样性高的化合物库,同时,为了高通量筛选平台不同课题的研究方向,潜在的靶点多样性也是非常重要的一方面。

世界上商品化的化合物约有5000万个, 我们只选择质量可靠,类药性佳,多样性好的化合物为客户提供实验样本。 在化合物库的设计和筛选过程中,我们通过一系列方法,保证化合物库的多样化和高度特异性。这些库已经在我们的内部生物检测中得到了广泛的验证,并且在超过200个外部合作伙伴的实验室中得到验证,其中包括美国、欧洲和日本的制药、生物技术、学术和筛选中心。

Diversity Pre-Plated Set AN2100 多样性预制化合物库 119877 compounds Pre-plated Diversity Sets LF1000 多样性核心预制库 50000 compounds Golden Scaffold Library L5610 Golden骨架库 10000 compounds SmartTM Library DO1200 药物靶点库 53200 compounds Structure Diversity Core Library DF4500 结构多样性核心库 50000 compounds Broadway Diversity Core Library VM1400 Broadway多样性核心库 25920 compounds Mini Scaffold Library L5600 Mini骨架库 5000 compounds DIVERSet-CL Library CB1000 CL多样性核心库 50000 compounds Fsp³-enriched Screening Compound Library LF7100 富含 Fsp³ 的筛选化合物库 51000 compounds Lead-like library OA1800 类先导化合物库 95000 compounds Unique Compounds Library US4300 特有化合物库 30000 compounds MCE-18 Trends in Medicinal Chemistry DP2180 2018药化趋势化合物库 50000 compounds Lead-like Compounds Library US3000 类先导化合物库US 30000 compounds Gold & Platinum Collections Library AN1200 结构多样性类药化合物库 261120 compounds Hit Locator Library From Enamine EN1200 苗头分子筛选库 460160 compounds Discovery Diversity Set2 From Enamine EN1100 药物发现多样性化合物库2 50240 compounds 3D-Pharmacophore Based Diversity Library DD5400 3D药效团多样性化合物库 50000 compounds 100k Diverse Compounds Pre-Plated Set DS7000 100K 多样性预制化合物库 111200 compounds Library “Avenue” VM1500 精选多样性化合物库 3400 compounds 3D Compound Libraries for HTS LF7200 3D 化合物库(用于HTS) 34500 compounds Diversity Libraries OA1500 Otava多样性化合物库 10000 compounds DIVERSet-EXP Library CB1100 EXP多样性库 50000 compounds Soluble Diversity Library DO1700 溶解多样性化合物库 9500 compounds Fast follow-up SAR diverse screening library DD5800 创新药SAR多样性筛选库 155000 compounds Saturated Compounds Library US3600 Fsp3多样性化合物库 16504 compounds World Diversity Set 3 SC1000 Specs多样性化合物库 10000 compounds DNA-encoded (DEL) Reagents and Building Blocks LF2800 DEL分子砌块化合物库 70000 compounds Targeted Diversity Library DP1400 靶点多样性化合物库 45000 compounds Beyond the Flatland Library sp3 enriched DO1000 sp3结构多样性化合物库 100000 compounds HTS Compound Library D3000 类药性化合物库 150000 compounds Scaffolds and Scaffold-based Compounds LF7500 骨架化合物库 140000 compounds Discovery Diversity Set1 From Enamine EN1000 药物发现多样性化合物库1 10240 compounds pre-plated HitFinder Collection MB1000 预制多样性化合物库MB 14400 compounds pre-plated HitCreator Collection MB1100 Maybridge多样性化合物库 14000 compounds BioDesign Library AN1000 生物核心结构库 170269 compounds Elite Library AN1100 精选先导化合物类似物库 91001 compounds Representative Compounds Library (Bemis-Murcko Clustering Algorithm) DD3700 代表性核心库(基于Bemis-Murcko Clustering算法) 300000 compounds Mixed Shapes Library US3200 形状多样性化合物库 837 compounds