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特色片段库

基于片段的筛选和药物发现(FBDD)已被证明是一种寻找新药的有效方法,适合先导化合物的发现,通过将筛选到的活性片段分子进行组合延伸得到新分子,获得更高活性的候选药物,此外,片段化合物分子量小,溶解度高等特点,更易进行结构优化,具有更好的成药潜力。TargetMol提供多种特色高品质的片段库,全方位满足各类客户需求。

High Solubility Pharmacophore Fragment Library L7830 高溶解性片段药效团化合物库 985 compounds High Solubility 3D Diversity Fragment Library L7850 高溶解性3D结构多样性片段化合物库 1079 compounds OA Chelator Fragment Library OA1300 螯合剂片段化合物库OA 2022 compounds High Solubility Polyfunctional Group Fragment Library L7810 高溶解性多官能团片段化合物库 1158 compounds Fluorinated Fragments Diversity Set EN8500 含氟片段多样性子库 1000 compounds Acrylamide Fragments EN8600 丙烯酰胺片段 2240 compounds Chloroacetamide Fragments EN8700 氯乙酰胺片段库 1360 compounds Cyanacrylamide Fragments EN8800 氰基丙烯酰胺片段库 800 compounds Butynamide Fragments EN8900 丁炔酰胺片段库 400 compounds Bicyclobutanes Library EN9000 双环丁烷库 320 compounds Sulfonyl Fluorides EN9100 磺酰氟片段库 960 compounds Disulfide Fragments EN9200 二硫化物片段库 320 compounds PPI Fragment Library From Enamine EN5200 蛋白相互作用片段化合物库 3600 compounds Single Pharmacophore Fragments From Enamine EN5300 单药效团片段化合物库 1500 compounds FRGx Fragments from Nature Library AC1100 天然片段化合物库 Carboxylic Acid Fragment Library From Enamine EN5400 羧酸片段化合物库 4000 compounds BIONET PROTAC Fragment Library BN2000 BIONET PROTAC片段库 644 compounds Natural Product-like Fragment Library LF8600 天然产物类似的片段化合物库 3100 compounds Halogen-enriched Fragment Library EN6400 富含卤素片段库 3000 compounds PPI Fragment Library LF8500 PPI 片段化合物库 10900 compounds Chelator Fragment Library LF8900 螯合剂片段化合物库 1580 compounds Fully Functionalized Probe Library From Enamine EN4900 全功能化探针化合物库 640 compounds Electrophilic Covalent Probe Library From Enamine EN5500 亲电共价探针化合物库 960 compounds High Fidelity Fragment Library From Enamine EN4400 高保真片段化合物库 1920 compounds High Solubility FragLite Fragment Library L7840 高溶解性卤化片段化合物库 796 compounds Fragments for RNA targets Library AN2600 靶向RNA片段化合物库 1065 compounds Drug-Fragment Library L8800 药物片段库 1119 compounds Natural Product-like Fragments From Enamine EN5000 天然产物类似片段化合物库 4160 compounds Carboxylic Acid Fragment Library With Solubility L7870 可溶性羧酸片段化合物库 1806 compounds Mini Electrophilic Heterocyclic Fragment Library L7860 Mini片段亲电杂环化合物库 369 compounds High Solubility Micro Fragment Library L7820 高溶解性微型片段化合物库 1081 compounds