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anti-liver_cancer_compound_library
/library/anti-liver_cancer_compound_library
抗肝癌化合物库
Anti-Liver Cancer Compound Library
产品编号: L2193

在全球范围内,肝癌占癌症死亡率第三位。肝癌的主要病因包括乙肝、丙肝、酒精性脂肪性肝炎和非酒精性脂肪性肝炎(NASH)。许多细胞信号通路与肝癌的发生有关,如 PI3K/Akt/mTOR 信号通路,表皮生长因子受体(EGFR)、血管内皮生长因子受体(VEGFR)等

TargetMol 抗肝癌化合物库收集了 2000 种与肝癌相关的化合物,包括已经报道具有肝癌治疗作用的化合物,以及靶向肝癌相关靶点潜在治疗肝癌的化合物,是抗肝癌药物研发的良好工具。

陶术生物的所有产品和服务仅用于科学研究,我们不为任何个人用途提供产品和服务。
产品编号:L2193
  • 2000种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究;
  • 通路靶点包含PI3K/Akt/mTOR,EGFR, FGFR,Met等;
  • 部分化合物已上市或进入临床期;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。
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化合物库组成
NF-κB (196)
PI3K (195)
VEGFR (146)
Reactive Oxygen Species (144)
EGFR (131)
Wnt/beta-catenin (109)
mTOR (107)
Akt (103)
JAK (93)
p38 MAPK (84)
GSK-3 (83)
ERK (81)
AMPK (81)
Endogenous Metabolite (78)
STAT (76)
FGFR (76)
Raf (73)
CDK (68)
Antibacterial (67)
c-Met/HGFR (62)
PDGFR (57)
Ras (51)
Kras (50)
TGF-beta/Smad (48)
Src (47)
MEK (47)
FLT (47)
JNK (45)
COX (45)
MAPK (40)
c-Kit (40)
IκB/IKK (38)
DNA-PK (33)
TNF (33)
HER (33)
DNA/RNA Synthesis (32)
S6 Kinase (30)
Parasite (29)
ATM/ATR (29)
Dehydrogenase (28)
HIV Protease (27)
IL Receptor (25)
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RIP kinase (23)
ALK (23)
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Aurora Kinase (22)
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Sigma receptor (1)
Thrombin (1)
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化合物库信息示例
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE