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anti_lung_cancer_compound_library
/library/anti_lung_cancer_compound_library
抗肺癌化合物库
Anti-Lung Cancer Compound Library
产品编号: L2190

根据《2018年全球癌症统计数据》报告,仅2018年,全球新增癌症病例1810万,死亡960万,其中亚洲占近70%,肺癌的发病率及死亡率居高不下(11.6%及18.4%)。肺癌的发病率和死亡率增长很快,对人群健康和生命威胁很大的恶性肿瘤之一。 由于缺乏有效的治疗手段,目前肺癌的治疗目标是延长生存期,尽可能长时间地实现和维持良好的生活质量。肺癌的治疗手段包括手术、放疗、化疗、免疫治疗或联合疗法。近年来,靶向治疗和肿瘤免疫疗法成为肺癌治疗的重要发展方向,并且取得了较好的治疗效果。但是靶向药物治疗易出现耐药性的问题,随着靶向药物的不断发展、全基因组测序的不断推进,开发新一代克服耐药的靶向治疗药物是肺癌药物开发的重中之重。 TargetMol 抗肺癌化合物库收集了2103 种与肺癌相关的化合物,包括已经报道有肺癌治疗作用的化合物,以及靶向肺癌相关靶点的化合物,是抗肺癌药物研发的良好工具。此外,我们还提供已知活性库、上市药物库、天然产物库以及一系列抗癌相关化合物库,可以用于抗癌药物的研发,如果您感兴趣,欢迎与我们联系~

陶术生物的所有产品和服务仅用于科学研究,我们不为任何个人用途提供产品和服务。
产品编号:L2190
  • 2103种与肺癌相关的化合物,可以用于抗肺癌药物研发和药理研究;
  • 靶点包含EGFR, PI3K, FGFR, HER2, ALK, c-Met等;
  • 部分化合物已上市或进入临床期;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。
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化合物库组成
Autophagy (193)
EGFR (183)
PI3K (177)
VEGFR (156)
mTOR (103)
JAK (102)
PDGFR (91)
FLT (90)
GSK-3 (80)
FGFR (80)
NF-κB (77)
c-Met/HGFR (67)
Akt (67)
c-Kit (67)
CDK (64)
ALK (63)
STAT (56)
Src (54)
Wnt/beta-catenin (54)
AMPK (50)
HER (50)
p53 (39)
DNA-PK (38)
Tyrosine Kinases (37)
IGF-1R (37)
TGF-beta/Smad (34)
Bcr-Abl (31)
Raf (30)
c-RET (30)
S6 Kinase (29)
ATM/ATR (28)
Aurora Kinase (25)
Others (23)
Pim (23)
DNA/RNA Synthesis (23)
TAM Receptor (23)
PDK (19)
Antibacterial (18)
Antibiotic (18)
FAK (17)
Mitophagy (16)
Parasite (16)
ERK (16)
HDAC (16)
PI4K (16)
MEK (16)
Potassium Channel (16)
Microtubule Associated (16)
Ferroptosis (15)
Trk receptor (15)
HIV Protease (14)
PKA (14)
PKC (14)
COX (14)
Kras (14)
c-Fms (14)
Mdm2 (13)
Dehydrogenase (13)
ADC Cytotoxin (12)
PARP (12)
Topoisomerase (12)
BTK (12)
Casein Kinase (12)
P450 (12)
ROS Kinase (12)
Chk (11)
MAPK (11)
5-HT Receptor (11)
TNF (11)
Syk (11)
HSP (10)
Endogenous Metabolite (10)
Phosphatase (9)
Nucleoside Antimetabolite/Analog (9)
Calcium Channel (9)
ROS (9)
IκB/IKK (9)
PPAR (8)
ROCK (8)
CSF-1R (8)
SIK (8)
Reactive Oxygen Species (8)
IL Receptor (8)
Histamine Receptor (7)
Adrenergic Receptor (7)
E1/E2/E3 Enzyme (7)
Drug Metabolite (7)
DNA Alkylation (7)
Interleukin (7)
Influenza Virus (7)
PLK (7)
AChR (7)
Histone Methyltransferase (6)
Estrogen/progestogen Receptor (6)
DYRK (6)
PDE (6)
MMP (6)
Epigenetic Reader Domain (6)
SARS-CoV (6)
MELK (6)
Sodium Channel (6)
p38 MAPK (5)
DNA Alkylator/Crosslinker (5)
Adenosine Receptor (5)
JNK (5)
Tie-2 (5)
Antifolate (5)
Glucocorticoid Receptor (5)
DUB (5)
Sirtuin (5)
Ras (5)
DHFR (4)
Dopamine Receptor (4)
HCV Protease (4)
Antifungal (4)
Histone Demethylase (4)
RAAS (4)
Virus Protease (4)
Rho (4)
PYK2 (4)
Caspase (4)
RIP kinase (4)
Gamma-secretase (4)
BCL (4)
Hedgehog/Smoothened (4)
GluR (4)
Lipoxygenase (4)
Antiviral (4)
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Ephrin Receptor (4)
Retinoid Receptor (4)
SGK (4)
MLK (4)
Proteasome (3)
Antioxidant (3)
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Serine Protease (3)
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Mitochondrial Metabolism (3)
HSV (3)
CCR (3)
PTEN (3)
ACK (3)
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TLR (3)
Histone Acetyltransferase (3)
Nrf2 (3)
Beta Amyloid (3)
Reverse Transcriptase (3)
Aromatase (3)
HIF (3)
Discoidin Domain Receptor (DDR) (3)
cholecystokinin (3)
Tyrosinase (3)
HIF/HIF Prolyl-Hydroxylase (3)
NO Synthase (3)
Carbonic Anhydrase (2)
Transferase (2)
Integrin (2)
Ligands for Target Protein for PROTAC (2)
YAP (2)
LTR (2)
GTPase (2)
Progesterone Receptor (2)
MRP (2)
Estrogen Receptor/ERR (2)
Serotonin Transporter (2)
Serine/threonin kinase (2)
TRP/TRPV Channel (2)
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IRE1 (2)
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Molecular Glues (2)
Opioid Receptor (2)
Smo (2)
Bombesin Receptor (2)
CXCR (2)
CaMK (2)
Indoleamine 2,3-Dioxygenase (IDO) (2)
MNK (2)
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transporter (2)
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Ligand for E3 Ligase (2)
ribosome (2)
GHSR (2)
DAPK (2)
IGF-2R (2)
DNA Methyltransferase (2)
IRAK (2)
Kinesin (2)
Melanin-concentrating Hormone Receptor (MCHR) (1)
ATPase (1)
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Adenylyl cyclase (1)
PROTACs (1)
NOS (1)
MALT (1)
ROR (1)
NEDD8 (1)
CRM1 (1)
MyD88 (1)
BACE (1)
Na+/Ca2+ Exchanger (1)
Reductase (1)
RAR/RXR  (1)
NADPH (1)
PERK (1)
Glutathione Peroxidase (1)
VDA (1)
c-Myc (1)
ABC (1)
HBV (1)
Hck (1)
Leukotriene Receptor (1)
Neurotensin Receptor (1)
Glucokinase (1)
Glutaminase (1)
MAO (1)
IDO (1)
iGluR (1)
Myosin (1)
MTH1 (1)
LDL (1)
Monoamine Transporter (1)
Guanylate cyclase (1)
Neuropeptide Y Receptor (1)
Fatty Acid Synthase (1)
Thioredoxin (1)
Xanthine Oxidase (1)
KSP (1)
cAMP (1)
Thrombopoietin Receptor (1)
DNA (1)
Androgen Receptor (1)
ATP Citrate Lyase (1)
Wee1 (1)
OXPHOS (1)
Beta-Secretase (1)
AChE (1)
Survivin (1)
Acyltransferase (1)
LRRK2 (1)
Free radical scavengers (1)
Decarboxylase (1)
PAI-1 (1)
Pyroptosis (1)
RSV (1)
Methionine Adenosyltransferase (MAT) (1)
GST (1)
CRISPR/Cas9 (1)
GPR (1)
Phospholipase (1)
GABA Receptor (1)
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Complement System (1)
Cannabinoid Receptor (1)
Gap Junction Protein (1)
Neurokinin receptor (1)
Platelet aggregation (1)
HMG-CoA Reductase (1)
Sigma receptor (1)
NOD-like Receptor (NLR) (1)
PD-1/PD-L1 (1)
Monoamine Oxidase (1)
S1P Receptor (1)
化合物库信息示例
Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE