高通量筛选天然产物库

Natural Product Library for HTS

产品编号： L6000

天然产物是由自然界中的生物体产生的化合物，它们的结构和功能在大自然漫长的进化过程中得以被选择和优化，并通过氧化态升降、骨架重排、阳离子环化、缩合反应以及周环反应等不同过程，产生了具有高度多样性的结构。这些独特的化学结构赋予了天然产物与靶点专一性结合的能力和良好的生物活性，成为发现治疗重大疾病药物的重要源泉，在现代药物研究中具有轰动效应的药物出现时，大都伴随着一种新类型天然产物的发现，这同时也推动了药物化学和生命科学的发展。

TargetMol 高通量筛选天然产物库精心挑选收录了4533 种天然产物单体，这些天然产物单体来源丰富，结构多样，具有很强的代表性。它们存在于三千余种中草药植物、动物以及微生物中提取纯化的天然来源中，涵盖了五百余种不同骨架结构和千余种靶点受体，大部分成分都达到对照品纯度。不仅如此，库中还包含了众多单价极高的稀有天然产物，性价比极高，是您在药物开发、药理研究、干细胞分化、指纹图谱研究、质量研究等领域的有力工具。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品编号：L6000

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

4533种天然产物的独特集合，是药物开发、药理研究、干细胞分化、指纹图谱研究、质量研究等领域的有力工具，可用于HTS和HCS；
提供产品的生物学信息和药物学信息，为筛选提供理论方向和研究基础；
来源清晰：精选来自动物、植物、微生物的已知活性天然产物；更具体到植物种属，并标注准确英文名或拉丁名，方便您的后期研究确证。
结构多样性好：4533种天然产物，含黄酮类、生物碱类在内的多种化合物类型，拥有详细的分类信息。
信息全面：从化合物结构到溶解度，从信号通路、作用靶点到生物活性信息均有详细描述。
可根据天然产物来源、天然产物类别、研究领域、药物市场状态等方面自由组合，高度定制。TargetMol天然产物库让高通量筛选更贴合您的研究方向！

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化合物库组成

NF-κB (196)

Antioxidant (169)

Antibiotic (155)

Antifungal (146)

Reactive Oxygen Species (106)

COX (104)

Parasite (95)

P450 (74)

TNF (73)

AChR (67)

Influenza Virus (66)

DNA/RNA Synthesis (61)

NO Synthase (60)

HIV Protease (58)

AChE (57)

IL Receptor (57)

GABA Receptor (53)

Anti-infection (52)

Calcium Channel (52)

ERK (50)

Akt (49)

PPAR (48)

Caspase (47)

p38 MAPK (47)

Tyrosinase (42)

STAT (42)

JAK (42)

AMPK (38)

ROS (36)

Antifection (36)

Virus Protease (36)

5-HT Receptor (35)

Ferroptosis (35)

Nrf2 (33)

MMP (33)

PI3K (33)

Dehydrogenase (33)

Microtubule Associated (32)

Lipoxygenase (31)

Immunology/Inflammation related (31)

JNK (30)

Topoisomerase (29)

PKC (29)

ATPase (28)

BCL (28)

TRP/TRPV Channel (28)

Beta Amyloid (27)

NOS (27)

Glucosidase (27)

Estrogen/progestogen Receptor (27)

Potassium Channel (26)

HSV (26)

Estrogen Receptor/ERR (26)

Antiviral (25)

P-gp (25)

Adrenergic Receptor (25)

Mitophagy (23)

ADC Cytotoxin (22)

PDE (22)

Prostaglandin Receptor (21)

PARP (21)

Sodium Channel (20)

HBV (20)

Dopamine Receptor (19)

Drug Metabolite (19)

Nucleoside Antimetabolite/Analog (19)

Wnt/beta-catenin (19)

Phosphatase (19)

HDAC (18)

EGFR (18)

Interleukin (17)

NMDAR (17)

MAO (17)

Phospholipase (15)

SARS-CoV (15)

mTOR (15)

Mitochondrial Metabolism (15)

Reductase (15)

Amino Acids and Derivatives (15)

HCV Protease (14)

GluR (14)

HIF/HIF Prolyl-Hydroxylase (13)

ribosome (13)

TLR (13)

Opioid Receptor (13)

iGluR (13)

Adenosine Receptor (13)

GPR (12)

TGF-beta/Smad (12)

CCR (12)

NOD (11)

Cannabinoid Receptor (11)

transporter (11)

MAPK (11)

CDK (11)

VEGFR (11)

Histamine Receptor (11)

RAAS (11)

Monoamine Oxidase (10)

Sirtuin (10)

Androgen Receptor (10)

Glucocorticoid Receptor (10)

BACE (10)

p53 (9)

HMG-CoA Reductase (9)

Platelet aggregation (9)

HIF (9)

IκB/IKK (9)

LDL (9)

FXR (9)

PKA (9)

MEK (8)

HSP (8)

Chloride channel (8)

Proteasome (8)

Fatty Acid Synthase (8)

UGT (8)

Aryl Hydrocarbon Receptor (8)

AhR (7)

Transferase (7)

Carbonic Anhydrase (7)

Xanthine Oxidase (7)

PAFR (7)

GSK-3 (7)

NOD-like Receptor (NLR) (6)

GST (6)

Beta-Secretase (6)

FAAH (6)

Gamma-secretase (6)

Arginase (6)

FAK (5)

Ras (5)

Aromatase (5)

Reverse Transcriptase (5)

Free radical scavengers (5)

Thyroid hormone receptor(THR) (5)

Indoleamine 2,3-Dioxygenase (IDO) (5)

DNA (5)

IGF-1R (5)

Epigenetic Reader Domain (5)

cAMP (5)

PTEN (5)

IAP (5)

Amylase (5)

Cysteine Protease (5)

Serine Protease (5)

Tyrosine Kinases (5)

MRP (5)

ABC (5)

NADPH (5)

Integrin (5)

HER (4)

DNA Methyltransferase (4)

Syk (4)

FGFR (4)

PDK (4)

Histone Acetyltransferase (4)

Aminopeptidase (4)

Src (4)

ROR (4)

PGE Synthase (4)

Lipid (4)

ATP Citrate Lyase (4)

CaMK (4)

Bombesin Receptor (4)

P2X Receptor (4)

Vitamin (4)

Liver X Receptor (4)

cell cycle arrest (4)

Serine/threonin kinase (4)

Imidazoline Receptor (3)

S6 Kinase (3)

Retinoid Receptor (3)

Trk receptor (3)

Acyltransferase (3)

Proton pump (3)

SGLT (3)

Telomerase (3)

CXCR (3)

Hedgehog/Smoothened (3)

Smo (3)

Monoamine Transporter (3)

DNA gyrase (3)

Phosphorylase (3)

Bcr-Abl (3)

E1/E2/E3 Enzyme (3)

Glucokinase (3)

Serotonin Transporter (3)

c-Myc (3)

Progesterone Receptor (3)

Glutathione Peroxidase (3)

LTR (3)

P2Y Receptor (3)

DNA Alkylator/Crosslinker (3)

c-Met/HGFR (3)

S1P Receptor (2)

PKM (2)

Thrombin (2)

IRAK (2)

NADPH-oxidase (2)

Neurokinin receptor (2)

PLK (2)

Oxytocin Receptor (2)

ATM/ATR (2)

RSV (2)

Casein Kinase (2)

Pyroptosis (2)

PAI-1 (2)

hCE (2)

GluCls (2)

Decarboxylase (2)

GPCR19 (2)

STING (2)

OAT (2)

Histone Methyltransferase (2)

DHFR (2)

NPC1L1 (2)

CAT (2)

Aurora Kinase (2)

PAK (2)

PDGFR (2)

DPP-4 (2)

Adiponectin receptor (2)

RANKL/RANK (2)

Leukotriene Receptor (2)

Pim (2)

gp120/CD4 (2)

Lipase (2)

Histone Demethylase (2)

DYRK (2)

PD-1/PD-L1 (1)

CFTR (1)

ROS Kinase (1)

cholecystokinin (1)

FLT (1)

NMU2R (1)

ATTECs (1)

Complement System (1)

Adenosine deaminase (1)

GHSR (1)

CRISPR/Cas9 (1)

ALK (1)

CRFR (1)

cGAS (1)

CPT (1)

AIM2 (1)

Dynamin (1)

CYP19A1 (1)

CD38 (1)

stilbene oxidase (1)

Hydrogenase (1)

Monocarboxylate transporter (1)

Transaminase (1)

Adenylyl cyclase (1)

Mdm2 (1)

advanced glycation end products (1)

Survivin (1)

Glutathione reductase (1)

BCRP (1)

Norepinephrine (1)

Thrombopoietin Receptor (1)

Epoxide Hydrolase (1)

PAD (1)

Somatostatin (1)

Chk (1)

Angiotensin-converting Enzyme (ACE) (1)

Bradykinin Receptor (1)

Vasopressin Receptor (1)

Stearoyl-CoA Desaturase (SCD) (1)

Hexokinase (1)

GlyT (1)

MT Receptor (1)

Glucagon Receptor (1)

Raf (1)

Fas/FasL (1)

MTH1 (1)

Annexin A (1)

IRE1 (1)

Prolyl Endopeptidase (PREP) (1)

IDO (1)

Glutaminase (1)

Neurotensin Receptor (1)

Antifolate (1)

CaSR (1)

OCT (1)

Melatonin Receptor (1)

Factor Xa (1)

PERK (1)

Cell wall (1)

RAR/RXR (1)

aconitase (1)

IFNAR (1)

LPL Receptor (1)

MyD88 (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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