血液病分子库 | L8400 | 陶术生物

血液病分子库

Hematonosis Compound Library

产品编号： L8400

血液病亦称为造血系统疾病，包括原发于造血系统疾病（如白血病原发于骨髓组织等）和主要累及造血系统疾病（如缺铁性贫血），例如白血病，血友病、再障、地中海贫血、骨髓增生异常综合症（MDS）、多发性骨髓瘤、淋巴瘤等。血液系统疾病多半是难治性疾病，发病隐袭，病状隐匿。由于缺乏特效疗法，许多疾病曾被称为“不治之症”，近年来，随着医学研究的深入发展，血液病的治疗效果有了明显提高。现代医学对血液病的治疗多应用激素、化疗等方法，但副作用大，病人治愈率低、易复发。骨髓移植用于治疗白血病，治愈率有所提高，然而骨髓资源十分缺乏，即使移植成功，5年内复发率也高达70%。因此寻找新的治疗方法和治疗药物具有重要意义。

TargetMol 作为全球知名化合物库供应商，积极关注科研动态，为您提供大量造血系统疾病研究相关的优质产品，为您的新药筛选提供一站式服务平台。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品编号：L8400

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

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产品描述

2405种造血系统疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
是研究造血系统功能及相关疾病的有效工具，例如白血病、血友病、β-地中海贫血等；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

PI3K (193)

EGFR (180)

JAK (127)

HDAC (126)

Wnt/beta-catenin (110)

mTOR (107)

Akt (103)

STAT (92)

FLT (86)

GSK-3 (83)

AMPK (83)

Antibacterial (74)

Endogenous Metabolite (72)

VEGFR (70)

CDK (68)

BCL (67)

Proteasome (61)

Bcr-Abl (61)

c-Kit (59)

BTK (54)

HIF/HIF Prolyl-Hydroxylase (54)

Histone Methyltransferase (53)

Src (52)

Others (51)

PDGFR (50)

HER (49)

COX (44)

HIF (44)

ERK (42)

Dehydrogenase (40)

Hedgehog/Smoothened (36)

DNA/RNA Synthesis (36)

HIV Protease (33)

DNA-PK (33)

Tyrosine Kinases (33)

Antibiotic (33)

TNF (32)

Reactive Oxygen Species (31)

S6 Kinase (31)

Caspase (30)

Epigenetic Reader Domain (30)

FGFR (30)

Parasite (29)

ATM/ATR (29)

p38 MAPK (28)

DNA Methyltransferase (25)

PKC (24)

Topoisomerase (24)

JNK (23)

Pim (23)

IL Receptor (23)

PDK (23)

PARP (22)

Aurora Kinase (22)

Potassium Channel (22)

c-Met/HGFR (21)

Mitophagy (21)

PPAR (21)

Gamma-secretase (20)

Ferroptosis (19)

Influenza Virus (19)

Microtubule Associated (19)

PD-1/PD-L1 (19)

c-Myc (18)

ALK (18)

c-RET (18)

Antifungal (17)

MEK (17)

TAM Receptor (17)

Virus Protease (16)

Raf (16)

CXCR (16)

IGF-1R (16)

MAPK (16)

PI4K (16)

P450 (16)

PKA (15)

E1/E2/E3 Enzyme (15)

Nrf2 (15)

Nucleoside Antimetabolite/Analog (14)

Calcium Channel (14)

DPP-4 (14)

HCV Protease (13)

Histone Demethylase (13)

Smo (13)

Chk (13)

Antiviral (13)

AChR (13)

p53 (13)

NO Synthase (13)

Antioxidant (12)

Lipoxygenase (12)

Trk receptor (12)

Casein Kinase (12)

IκB/IKK (12)

Beta Amyloid (12)

Phosphatase (11)

Isocitrate Dehydrogenase (IDH) (11)

MMP (11)

Interleukin (11)

c-Fms (11)

ADC Cytotoxin (10)

TLR (10)

PLK (10)

Syk (10)

NOS (9)

PDE (9)

ROS (9)

P-gp (9)

HSP (9)

Adenosine Receptor (8)

CSF-1R (8)

SIK (8)

PTEN (8)

Sirtuin (8)

GABA Receptor (8)

FAK (8)

DNA Alkylator/Crosslinker (7)

DYRK (7)

ROCK (7)

Drug Metabolite (7)

Mitochondrial Metabolism (7)

Antifection (7)

DNA Alkylation (7)

Histone Acetyltransferase (7)

5-HT Receptor (7)

Sodium Channel (7)

Mdm2 (6)

Rho (6)

Cysteine Protease (6)

HSV (6)

DUB (6)

TGF-beta/Smad (6)

Prostaglandin Receptor (6)

SARS-CoV (6)

Retinoid Receptor (6)

Anti-infection (6)

IRAK (6)

Tyrosinase (6)

Estrogen/progestogen Receptor (5)

Adrenergic Receptor (5)

Immunology/Inflammation related (5)

IAP (5)

transporter (5)

MELK (5)

Cannabinoid Receptor (5)

Ras (5)

ROS Kinase (5)

Chloride channel (4)

ATPase (4)

Carbonic Anhydrase (4)

Integrin (4)

Histamine Receptor (4)

HBV (4)

TRP/TRPV Channel (4)

CCR (4)

GluR (4)

CaMK (4)

AChE (4)

Porcupine (4)

Aminopeptidase (4)

SGK (4)

S1P Receptor (4)

Transferase (3)

DHFR (3)

Dopamine Receptor (3)

LTR (3)

BACE (3)

IFNAR (3)

NADPH (3)

RAAS (3)

Tie-2 (3)

GTPase (3)

Estrogen Receptor/ERR (3)

Serine/threonin kinase (3)

MAO (3)

IRE1 (3)

UGT (3)

LDL (3)

NMDAR (3)

Glucosidase (3)

PAK (3)

ACK (3)

Lipid (3)

BCRP (3)

PGE Synthase (3)

Acyltransferase (3)

MNK (3)

Ephrin Receptor (3)

Methionine Adenosyltransferase (MAT) (3)

Reverse Transcriptase (3)

Adenosine deaminase (3)

Cuproptosis (3)

NOD (3)

NOD-like Receptor (NLR) (3)

Kinesin (3)

NEDD8 (2)

CRM1 (2)

Amino Acids and Derivatives (2)

Glutathione Peroxidase (2)

TOPK (2)

Hck (2)

Serine Protease (2)

Antifolate (2)

Liver X Receptor (2)

Leukotriene Receptor (2)

NAMPT (2)

PYK2 (2)

Aryl Hydrocarbon Receptor (2)

RIP kinase (2)

GRK (2)

Monoamine Transporter (2)

Opioid Receptor (2)

Fatty Acid Synthase (2)

PAD (2)

KSP (2)

cAMP (2)

Androgen Receptor (2)

SGLT (2)

ATP Citrate Lyase (2)

Beta-Secretase (2)

Survivin (2)

CRISPR/Cas9 (2)

GPR (2)

Phospholipase (2)

DAPK (2)

Discoidin Domain Receptor (DDR) (2)

cholecystokinin (2)

Thrombin (2)

AhR (2)

MLK (2)

Melanin-concentrating Hormone Receptor (MCHR) (1)

Proton pump (1)

Adenylyl cyclase (1)

PROTACs (1)

NPC1L1 (1)

Monocarboxylate transporter (1)

MALT (1)

ROR (1)

NUDIX hydrolase (1)

MyD88 (1)

YAP (1)

Arginase (1)

LPL Receptor (1)

Reductase (1)

Na+/Ca2+ Exchanger (1)

RAR/RXR (1)

Lipase (1)

PERK (1)

gp120/CD4 (1)

Factor Xa (1)

Progesterone Receptor (1)

OCT (1)

ABC (1)

MRP (1)

FXR (1)

Glucokinase (1)

Glutaminase (1)

Glucocorticoid Receptor (1)

Myosin (1)

Haspin Kinase (1)

DNA gyrase (1)

Guanylate cyclase (1)

Thrombopoietin Receptor (1)

DNA (1)

Telomerase (1)

Wee1 (1)

OXPHOS (1)

STING (1)

LRRK2 (1)

Free radical scavengers (1)

Decarboxylase (1)

hCE (1)

RSV (1)

Hippo pathway (1)

Neprilysin (1)

GST (1)

Protease (1)

Aromatase (1)

KLF (1)

Platelet aggregation (1)

NADPH-oxidase (1)

BMI-1 (1)

Sigma receptor (1)

Protease-activated Receptor (1)

p97 (1)

CFTR (1)

Imidazoline Receptor (1)

Monoamine Oxidase (1)

PKM (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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