FDA 上市药物库 | L4200 | 陶术生物

FDA 上市药物库

FDA-Approved Drug Library

产品编号： L4200

FDA 上市药物库中的所有化合物都具有良好的生物活性、明确的靶点信息，较好的安全性和生物利用度，这些特性可显著加速药物开发和优化，是进行小分子细胞诱导分化和药物重定位理想的工具。详尽的数据资料可以帮助科学家快速完成药物筛选或细胞诱导机制的判断，并为深入揭示其机制机理创造条件。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品编号：L4200

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

SDF

产品描述

1840个FDA批准药物的独特集合，可用于高通量筛选和高内涵筛选；
全部得到FDA批准，提供FDA批准编号，用于药物重定位、新的药物靶点筛选的有效工具；
经过了严格的临床前研究和临床试验，生物活性和安全性得到保障；
涵盖多个研究领域：肿瘤、心血管药物、抗炎、免疫、神经系统药物、呼吸系统药物等；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

化合物库定制

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化合物库咨询

化合物库组成

Apoptosis (170)

Endogenous Metabolite (134)

Adrenergic Receptor (121)

5-HT Receptor (116)

Others (98)

AChR (89)

Histamine Receptor (78)

Dopamine Receptor (72)

HIV Protease (70)

Sodium Channel (60)

COX (58)

Antifungal (57)

Parasite (57)

Potassium Channel (53)

DNA/RNA Synthesis (52)

Glucocorticoid Receptor (51)

Estrogen/progestogen Receptor (41)

Calcium Channel (38)

Topoisomerase (34)

Cytochromes P450 (34)

Ferroptosis (32)

RAAS (32)

SARS-CoV (32)

Serotonin Transporter (27)

VEGFR (26)

PDE (25)

ribosome (25)

Dehydrogenase (24)

Estrogen Receptor/ERR (24)

Microtubule Associated (24)

Mitophagy (23)

Norepinephrine (23)

c-Kit (23)

Nucleoside Antimetabolite/Analog (22)

Reverse Transcriptase (22)

GABA Receptor (22)

HCV Protease (21)

Antifection (21)

Progesterone Receptor (20)

HSV (20)

EGFR (20)

PPAR (19)

PDGFR (19)

Proton pump (17)

Reactive Oxygen Species (17)

ADC Cytotoxin (16)

Androgen Receptor (16)

Influenza Virus (16)

ATPase (15)

Carbonic Anhydrase (15)

HBV (15)

JAK (15)

Cholinesterase (ChE) (14)

Prostaglandin Receptor (14)

Src (13)

Phosphatase (13)

MAO (13)

FGFR (13)

FLT (13)

Thrombin (13)

Proteasome (12)

DNA Alkylator/Crosslinker (12)

Adenosine Receptor (12)

Bcr-Abl (12)

Thyroid hormone receptor(THR) (11)

c-Met/HGFR (11)

MRP (11)

Tyrosine Kinases (11)

ROS (11)

NF-κB (11)

HMG-CoA Reductase (11)

Transferase (10)

DHFR (10)

Virus Protease (10)

PARP (10)

Antifolate (10)

ALK (10)

HDAC (10)

c-RET (10)

Monoamine Oxidase (10)

GNRH Receptor (9)

TRP/TRPV Channel (9)

iGluR (9)

Raf (9)

Drug Metabolite (9)

Opioid Receptor (9)

MMP (9)

SGLT (9)

NO Synthase (9)

PI3K (8)

ABC Transporter (8)

GluR (8)

P-gp (8)

Retinoid Receptor (8)

P2Y Receptor (7)

Factor Xa (7)

PKC (7)

CDK (7)

NMDAR (7)

DNA gyrase (7)

Guanylate cyclase (7)

DPP-4 (7)

Endothelin Receptor (7)

CaMK (7)

mTOR (7)

STAT (7)

Phospholipase (7)

DNA Methyltransferase (7)

HIF/HIF Prolyl-Hydroxylase (7)

LPL Receptor (6)

DNA Alkylation (6)

IL Receptor (6)

TLR (6)

Trk receptor (6)

MEK (6)

TNF (6)

HER (6)

S1P Receptor (6)

Histone Methyltransferase (5)

Integrin (5)

Cell wall (5)

NADPH (5)

Monoamine Transporter (5)

Hedgehog/Smoothened (5)

Vasopressin Receptor (5)

Lipoxygenase (5)

Antiviral (5)

Nrf2 (5)

Neurokinin receptor (5)

TAM Receptor (5)

ROS Kinase (5)

CFTR (5)

Amino Acids and Derivatives (4)

Reductase (4)

Glutathione Peroxidase (4)

FXR (4)

Vitamin (4)

ROCK (4)

Annexin A (4)

Molecular Glues (4)

Isocitrate Dehydrogenase (IDH) (4)

Interleukin (4)

HSP (4)

Ligand for E3 Ligase (4)

Aromatase (4)

GPR (4)

AMPK (4)

Hydroxylase (4)

HIF (4)

AhR (4)

NOS (3)

Histone Demethylase (3)

CaSR (3)

Cysteine Protease (3)

ERK (3)

Aryl Hydrocarbon Receptor (3)

LDL (3)

MT Receptor (3)

Mitochondrial Metabolism (3)

BTK (3)

Smo (3)

Fatty Acid Synthase (3)

PAK (3)

IGF-1R (3)

DNA (3)

GPCR19 (3)

Bcl-2 Family (3)

Decarboxylase (3)

Neprilysin (3)

GST (3)

Melanocortin Receptor (3)

Complement System (3)

Sigma receptor (3)

cholecystokinin (3)

Chloride channel (2)

CRM1 (2)

Ligands for Target Protein for PROTAC (2)

Arginase (2)

Antioxidant (2)

CETP (2)

GSK-3 (2)

Melatonin Receptor (2)

Rho (2)

Leukotriene Receptor (2)

Caspase (2)

IRE1 (2)

UGT (2)

Gamma-secretase (2)

P2X Receptor (2)

Na-K-Cl cotransporter (2)

Integrase (2)

CCR (2)

CXCR (2)

Xanthine Oxidase (2)

Thrombopoietin Receptor (2)

Akt (2)

Beta-Secretase (2)

PGE Synthase (2)

Glutathione reductase (2)

Free radical scavengers (2)

Ephrin Receptor (2)

GluCls (2)

RSV (2)

Beta Amyloid (2)

Kras (2)

c-Fms (2)

Adenosine Deaminase (2)

CGRP Receptor (2)

Gap Junction Protein (2)

Syk (2)

Ras (2)

Protease-activated Receptor (2)

PKM (2)

NPC1L1 (1)

Hydrogenase (1)

ROR (1)

DNA-PK (1)

YAP (1)

IFNAR (1)

RAR/RXR (1)

gp120/CD4 (1)

TOPK (1)

VDA (1)

PKA (1)

Wnt/beta-catenin (1)

Serine Protease (1)

IAP (1)

CSF-1R (1)

Myosin (1)

Adiponectin Receptor (1)

MTH1 (1)

GRK (1)

Glucagon Receptor (1)

Phosphorylase (1)

GlyT (1)

Glucosidase (1)

PROTAC Linker (1)

HCN Channel (1)

FAAH (1)

Bradykinin Receptor (1)

ACK1 (1)

Angiotensin-converting Enzyme (ACE) (1)

Somatostatin (1)

Chk (1)

Epigenetic Reader Domain (1)

DUB (1)

Telomerase (1)

TGF-beta/Smad (1)

ATP Citrate Lyase (1)

Lipid (1)

MAPK (1)

OAT (1)

STING (1)

Pyroptosis (1)

IκB/IKK (1)

CRISPR/Cas9 (1)

PDK (1)

Oxytocin Receptor (1)

Aquaporin (1)

PLK (1)

Platelet aggregation (1)

Anti-infection (1)

NADPH-oxidase (1)

Tyrosinase (1)

NOD-like Receptor (NLR) (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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