内分泌激素分子库 | L2400 | 陶术生物

内分泌激素分子库

Endocrinology-Hormone Compound Library

产品编号： L2400

内分泌腺是由一群合成并释放激素的细胞组成，激素随体液输送到靶细胞起作用，调节生长、发育、繁殖和代谢活动，维持内环境的稳态。常见的激素有甲状腺激素、肾上腺素、胰岛素、性激素等，根据化学结构不同，激素通常分为蛋白类、固醇类和氨基酸衍生物，不同激素的受体不同，作用方式不同。内分泌系统的疾病可由激素的过度分泌或分泌不足或目标器官或组织无法有效应对激素引起。

TargetMol 内分泌激素分子库包含924 个与内分泌系统及其信号通路相关的小分子化合物，用于人体内分泌系统的研究及相关疾病的药物筛选，可用于高通量、高内涵筛选。

陶术生物的所有产品和服务仅用于科学研究，我们不为任何个人用途提供产品和服务。

产品编号：L2400

技术资料

陶术生物化合物库目录(28.1MB)

库化合物信息

Excel

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产品描述

924种与内分泌系统相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
是研究人体内分泌系统疾病和筛选相关药物的有效工具；
靶点含雌激素受体、甲状腺激素受体、去甲肾上腺素受体等等；
结构多样，药效显著，可渗透细胞；
详细的说明书，化合物结构、靶点信息、IC50值、活性描述等；
NMR、HPLC/LCMS等多种检测技术保证产品结构正确，纯度高，减少假阳性。

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化合物库组成

Estrogen/progestogen Receptor (76)

Dopamine Receptor (74)

RAAS (62)

5-HT Receptor (62)

Estrogen Receptor/ERR (60)

Androgen Receptor (60)

GPR (57)

Glucocorticoid Receptor (55)

Autophagy (44)

Apoptosis (42)

Opioid Receptor (33)

Histamine Receptor (24)

Prostaglandin Receptor (23)

AChR (23)

IGF-1R (20)

Thyroid hormone receptor(THR) (19)

Reductase (18)

Progesterone Receptor (16)

Endogenous Metabolite (13)

Norepinephrine (12)

Aromatase (12)

P450 (12)

Vasopressin Receptor (11)

GHSR (10)

Calcium Channel (9)

Potassium Channel (9)

ADC Cytotoxin (8)

Antibacterial (8)

Serotonin Transporter (7)

COX (7)

PDE (6)

HSP (6)

TSH Receptor (6)

Antibiotic (5)

MRP (4)

PPAR (4)

VEGFR (4)

Drug Metabolite (4)

Reactive Oxygen Species (4)

Endothelin Receptor (4)

OX Receptor (4)

CaMK (4)

Influenza Virus (4)

Cannabinoid Receptor (4)

Sigma receptor (4)

Thrombin (4)

Src (3)

Others (3)

Antifungal (3)

c-Met/HGFR (3)

GNRH Receptor (3)

Parasite (3)

GluR (3)

P-gp (3)

SARS-CoV (3)

Trk receptor (3)

ALK (3)

NF-κB (3)

Oxytocin Receptor (3)

FGFR (3)

Sodium Channel (3)

HIV Protease (2)

Dehydrogenase (2)

PI3K (2)

Mitophagy (2)

Phosphatase (2)

Virus Protease (2)

Serine Protease (2)

Cysteine Protease (2)

TRP/TRPV Channel (2)

PKC (2)

Smo (2)

PDGFR (2)

EGFR (2)

Acyltransferase (2)

STAT (2)

Phospholipase (2)

MEK (2)

Gap Junction Protein (2)

Syk (2)

IGF-2R (2)

FAK (2)

AhR (2)

Imidazoline Receptor (2)

Melanin-concentrating Hormone Receptor (MCHR) (1)

advanced glycation end products (1)

Apelin receptor (1)

Chloride channel (1)

ATPase (1)

Adenylyl cyclase (1)

Transferase (1)

Histone Methyltransferase (1)

HCV Protease (1)

Integrin (1)

p38 MAPK (1)

Ferroptosis (1)

P2Y Receptor (1)

Arrestin (1)

RAR/RXR (1)

NADPH (1)

JNK (1)

ABC (1)

CaSR (1)

HBV (1)

Tyrosine Kinases (1)

Rho (1)

Liver X Receptor (1)

PYK2 (1)

ROCK (1)

ERK (1)

MAO (1)

iGluR (1)

Topoisomerase (1)

Annexin A (1)

Bcr-Abl (1)

LDL (1)

CDK (1)

Raf (1)

Glucagon Receptor (1)

NMDAR (1)

Mitochondrial Metabolism (1)

Monoamine Transporter (1)

ROS (1)

HCN Channel (1)

DNA Alkylation (1)

HSV (1)

IL Receptor (1)

Angiotensin-converting Enzyme (ACE) (1)

Aurora Kinase (1)

Thrombopoietin Receptor (1)

Epigenetic Reader Domain (1)

DNA (1)

mTOR (1)

Interleukin (1)

Akt (1)

AChE (1)

Antiviral (1)

LRRK2 (1)

GPCR19 (1)

Free radical scavengers (1)

Histone Acetyltransferase (1)

Neprilysin (1)

GST (1)

Acetyl-CoA Carboxylase (1)

Beta Amyloid (1)

Retinoid Receptor (1)

CRISPR/Cas9 (1)

GABA Receptor (1)

Hydroxylase (1)

CGRP Receptor (1)

SGK (1)

TNF (1)

Complement System (1)

Platelet aggregation (1)

FLT (1)

S6 Kinase (1)

MLK (1)

Monoamine Oxidase (1)

NO Synthase (1)

化合物库信息示例

Empty	1000025-07-9	1000413-72-8	229005-80-5	1000787-75-6	946387-07-1	1000998-59-3	1175526-27-8	1001288-58-9	1001350-96-4	1001404-83-6	Empty
Empty	Vadadustat	TAK875	TAK-779	Tegobuvir	RN-1734	BMS-687453	AM211	FT011	BMS754807	AAI101	Empty
Empty	1001625-82-6	1001645-58-4	1001753-24-7	1001908-89-9	1002304-34-8	1002-84-2	100291-86-9	100299-08-9	10030-52-1	10040-45-6	Empty
Empty	RPW-24	SRT1720 hydrochloride	INH6	SRT 2183	AMG208	Pentadecanoic acid	Apiopaeonoside	Pemirolast potassium	L-Anserine nitrate salt	Sodium Picosulfate	Empty
Empty	100427-26-7	1004316-88-4	10045-45-1	100462-37-1	1004990-28-6	100-51-6	1005-24-9	1005264-47-0	1005334-57-5	1005342-46-0	Empty
Empty	Lercanidipine	Cobicistat	1-Ethyl-2-benzimidazolinone	ROSIRIDIN	PF-AKT400	Benzyl alcohol	1-Methylnicotinamide chloride	MX69	CVT-10216	LCL161	Empty
Empty	1005491-05-3	100-55-0	1005504-62-0	1005883-72-6	100643-71-8	1007207-67-1	10075-50-0	1007647-73-5	100784-20-1	10083-24-6	Empty
Empty	Tirasemtiv	Roniacol	Rg3039	Z433927330	Desloratadine	CH5132799	5-Bromoindole	Smurf1-IN-A01	Halosulfuron-methyl	Piceatannol	Empty
Empty	100872-83-1	100874-08-6	1009119-64-5	1009119-65-6	100929-71-3	1009298-09-2	1009298-59-2	100929-99-5	1009734-33-1	10097-84-4	Empty
Empty	ML346	SB 4	Daclatasvir	Daclatasvir dihydrochloride	NADPH (tetracyclohexanamine)	AZD8055	Vistusertib	PAβN dihydrochloride	HZ1157	Rotundine	Empty
Empty	1009816-48-1	1009817-63-3	1009820-21-6	100986-85-4	101001-34-7	1010411-21-8	1010-60-2	1011244-68-0	1011301-27-1	1011529-10-4	Empty
Empty	Thiamet G	B-AP15	Silmitasertib	Levofloxacin	Pamicogrel	GSK369796 Dihydrochloride	2-Chloronaphthoquinone	TFAP	Tenovin3	Azvudine	Empty
Empty	101152-94-7	101155-02-6	1011557-82-6	1011-74-1	101-20-2	1012054-59-9	101-21-3	101-26-8	101303-98-4	1013101-36-4	Empty
Empty	Milnacipran hydrochloride	BW-A78U	Tenovin-6	DL-Normetanephrine hydrochloride	Triclocarban	CUDC101	Chlorpropham	Mestinon	Zacopride hydrochloride	PF04691502	Empty
Empty	101-31-5	1013-69-0	1013750-77-0	1013753-99-5	10138-52-0	1013920-15-4	1013937-63-7	1014691-61-2	101477-54-7	101494-95-5	Empty
Empty	L-Hyoscyamine	Noreugenin	ML-030	BC-1382	Gadolinium chloride	Vorolanib	VTP-27999 TFA	GSK0660	Lomerizine hydrochloride	8-CHLOROQUINAZOLIN-4(1H)-ONE	Empty

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